mtROS-Induced TRPV4 Activation in Traumatic Brain Injury
نویسندگان
چکیده
منابع مشابه
Biomechanical analysis of blast-induced traumatic brain injury
Purpose: Blast-induced traumatic brain injury (bTBI) is one of the causes of death or permanent invalidity which can occur unexpectedly in both military and civilian populations. This study set out to conduct a combined Eulerian-Lagrangian computational analysis of the interaction between a single planar blast wave and a human head in order to assess the extent of intracranial shock w...
متن کاملP108: Microglia in Traumatic Brain Injury
Microglia is one of the first innate immune components. These cells account about 5 to 10% of the entire adult brain cells and are activated by trauma. Complex-mediated inflammatory responses occur through cellular and molecular events during and after the traumatic brain injury (TBI). In-lesion area astrocytes, microglia, and damaged neurons begin to secrete cytokines and chemokines. Microglia...
متن کاملMicroglial Activation in Traumatic Brain Injury
Microglia have a variety of functions in the brain, including synaptic pruning, CNS repair and mediating the immune response against peripheral infection. Microglia rapidly become activated in response to CNS damage. Depending on the nature of the stimulus, microglia can take a number of activation states, which correspond to altered microglia morphology, gene expression and function. It has be...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2019
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2018.5847